PDLIM4

PDZ and LIM domain protein 4 is a protein that in humans is encoded by the PDLIM4 gene.^[5][6]

PDLIM4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2EEG, 2V1W, 4Q2O
Identifiers
Aliases	PDLIM4, RIL, PDZ and LIM domain 4
External IDs	OMIM: 603422; MGI: 1353470; HomoloGene: 2735; GeneCards: PDLIM4; OMA:PDLIM4 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q31.1 Start 132,257,696 bp[1] End 132,273,454 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B1.3|11 32.13 cM Start 53,945,754 bp[2] End 53,959,840 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left uterine tube body of uterus tibial nerve muscle layer of sigmoid colon cartilage tissue skin of leg gastric mucosa skin of abdomen ascending aorta Descending thoracic aorta Top expressed in lip body wall condyle uterus epithelium of stomach stroma of bone marrow calvaria ankle joint molar cervix More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding protein binding protein phosphatase binding protein homodimerization activity alpha-actinin binding actin binding muscle alpha-actinin binding Cellular component stress fiber early endosome lumen filamentous actin recycling endosome lumen postsynaptic membrane nucleus cytoplasm endosome cytoskeleton membrane lamellipodium cell junction early endosome membrane cell projection neuron projection dendritic spine synapse perinuclear region of cytoplasm recycling endosome membrane Z discdkac Biological process actin cytoskeleton reorganization excitatory chemical synaptic transmission heart development actin cytoskeleton organization muscle structure development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8572 30794 Ensembl ENSG00000131435 ENSMUSG00000020388 UniProt P50479 P70271 RefSeq (mRNA) NM_003687 NM_001131027 NM_019417 RefSeq (protein) NP_001124499 NP_003678 NP_062290 Location (UCSC) Chr 5: 132.26 – 132.27 Mb Chr 11: 53.95 – 53.96 Mb PubMed search [3] [4]
Wikidata
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