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PDSS2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

PDSS2
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Decaprenyl-diphosphate synthase subunit 2 (PDSS2) is a protein that in humans is encoded by the PDSS2 gene.[5]

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Function

The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis.[5]

Clinical significance

It may be associated with Coenzyme Q10 deficiency.[6]

See also

References

Further reading

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