PELI2

Protein pellino homolog 2 is a protein that in humans is encoded by the PELI2 gene.^[5][6][7]

PELI2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3EGA, 3EGB
Identifiers
Aliases	PELI2, pellino E3 ubiquitin protein ligase family member 2
External IDs	OMIM: 614798; MGI: 1891445; HomoloGene: 41431; GeneCards: PELI2; OMA:PELI2 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q22.3 Start 56,117,814 bp[1] End 56,301,524 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14 C1|14 24.6 cM Start 48,358,280 bp[2] End 48,519,032 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone testicle ganglionic eminence Achilles tendon jejunal mucosa monocyte body of pancreas metanephric glomerulus blood sural nerve Top expressed in basilar part of occipital bone spermatid fibula splanchnocranium seminiferous tubule spermatocyte Meckel's cartilage sciatic nerve ascending aorta aortic valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding ubiquitin-ubiquitin ligase activity protein serine/threonine kinase activity transferase activity ubiquitin protein ligase activity Cellular component cytosol Biological process positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of protein phosphorylation protein ubiquitination positive regulation of MAPK cascade protein polyubiquitination protein phosphorylation immune response Toll signaling pathway interleukin-1-mediated signaling pathway regulation of Toll signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57161 93834 Ensembl ENSG00000139946 ENSMUSG00000021846 UniProt Q9HAT8 Q8BST6 RefSeq (mRNA) NM_021255 NM_033602 RefSeq (protein) NP_067078 NP_291080 Location (UCSC) Chr 14: 56.12 – 56.3 Mb Chr 14: 48.36 – 48.52 Mb PubMed search [3] [4]
Wikidata
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