Top Qs
Timeline
Chat
Perspective
PFKFB1
Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia
Remove ads
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene.[5][6]
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.[6]
Remove ads
References
Further reading
Wikiwand - on
Seamless Wikipedia browsing. On steroids.
Remove ads