PHF12

PHD finger protein 12 is a protein that in humans is encoded by the PHF12 gene.^[5][6]

PHF12
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2L9S, 2LKM
Identifiers
Aliases	PHF12, PF1, PHD finger protein 12
External IDs	MGI: 1924057; HomoloGene: 10841; GeneCards: PHF12; OMA:PHF12 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q11.2 Start 28,905,250 bp[1] End 28,951,771 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B5 Start 77,873,580 bp[2] End 77,921,365 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve granulocyte bone marrow cells stromal cell of endometrium spleen right lung blood appendix gastric mucosa ganglionic eminence Top expressed in genital tubercle tail of embryo neural layer of retina granulocyte ventricular zone zygote superior frontal gyrus dentate gyrus of hippocampal formation granule cell thymus secondary oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transcription corepressor binding histone binding transcription corepressor activity RNA polymerase II transcription regulatory region sequence-specific DNA binding chromatin binding protein binding phosphatidylinositol binding metal ion binding Cellular component transcription repressor complex Sin3 complex nucleus nucleoplasm Sin3-type complex Biological process negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57649 268448 Ensembl ENSG00000109118 ENSMUSG00000037791 UniProt Q96QT6 Q5SPL2 RefSeq (mRNA) NM_001033561 NM_001290131 NM_020889 NM_174852 RefSeq (protein) NP_001028733 NP_001277060 NP_065940 NP_777277 Location (UCSC) Chr 17: 28.91 – 28.95 Mb Chr 11: 77.87 – 77.92 Mb PubMed search [3] [4]
Wikidata
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Interactions

PHF12 has been shown to interact with SIN3A.^[5]