PHLPPL

PH domain and leucine rich repeat protein phosphatase-like, also known as PHLPPL, is an enzyme which in humans is encoded by the PHLPPL gene.^[5]

PHLPP2
Identifiers
Aliases	PHLPP2, PHLPPL, PPM3B, PH domain and leucine rich repeat protein phosphatase 2
External IDs	OMIM: 611066; MGI: 2444928; HomoloGene: 71015; GeneCards: PHLPP2; OMA:PHLPP2 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q22.2 Start 71,637,835 bp[1] End 71,724,701 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 D3 Start 110,595,174 bp[2] End 110,671,303 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of ileum jejunal mucosa mucosa of colon mucosa of sigmoid colon middle temporal gyrus retinal pigment epithelium germinal epithelium Brodmann area 46 duodenum mucosa of transverse colon Top expressed in retinal pigment epithelium left colon neural layer of retina dorsomedial hypothalamic nucleus jejunum hand ciliary body substantia nigra paraventricular nucleus of hypothalamus ventral tegmental area More reference expression data BioGPS More reference expression data
Gene ontology Molecular function catalytic activity phosphoprotein phosphatase activity hydrolase activity metal ion binding protein binding protein serine/threonine phosphatase activity Cellular component cytoplasm cytosol membrane nucleus photoreceptor inner segment photoreceptor outer segment membrane Biological process hippocampus development protein dephosphorylation signal transduction negative regulation of protein kinase B signaling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23035 244650 Ensembl ENSG00000040199 ENSMUSG00000031732 UniProt Q6ZVD8 Q8BXA7 RefSeq (mRNA) NM_015020 NM_001289003 NM_001122594 RefSeq (protein) NP_001275932 NP_055835 NP_001116066 Location (UCSC) Chr 16: 71.64 – 71.72 Mb Chr 8: 110.6 – 110.67 Mb PubMed search [3] [4]
Wikidata
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See also

• PHLPP