PIBF1

Progesterone-induced-blocking factor 1 is a protein that in humans is encoded by the PIBF1 gene.^[4][5] It has been shown to localize to the centrosome^[6] and has also been named CEP90.^[7]

PIBF1
Identifiers
Aliases	PIBF1, C13orf24, CEP90, PIBF, progesterone immunomodulatory binding factor 1, JBTS33
External IDs	OMIM: 607532; MGI: 1261910; HomoloGene: 4628; GeneCards: PIBF1; OMA:PIBF1 - orthologs
Gene location (Mouse) Chr. Chromosome 14 (mouse)[1] Band 14 E2.2|14 49.27 cM Start 99,336,860 bp[1] End 99,491,929 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon sural nerve bronchial epithelial cell ganglionic eminence right lobe of thyroid gland stromal cell of endometrium right uterine tube left lobe of thyroid gland anterior pituitary canal of the cervix Top expressed in spermatocyte spermatid zygote genital tubercle tail of embryo secondary oocyte seminiferous tubule morula blastocyst granulocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function interleukin-4 receptor binding protein binding Cellular component cytoplasm centrosome centriolar satellite extracellular region cytoskeleton nucleus extracellular space microtubule organizing center Biological process negative regulation of natural killer cell activation positive regulation of interleukin-10 production immune system process mitotic spindle assembly protein localization to centrosome mitotic metaphase plate congression negative regulation of prostaglandin biosynthetic process negative regulation of interleukin-12 production non-motile cilium assembly positive regulation of tyrosine phosphorylation of STAT protein negative regulation of tyrosine phosphorylation of STAT protein activation of Janus kinase activity cilium assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10464 52023 Ensembl n/a ENSMUSG00000022064 UniProt Q8WXW3 n/a RefSeq (mRNA) NM_006346 NM_001349655 NM_029320 NM_029454 RefSeq (protein) NP_006337 NP_001336584 n/a Location (UCSC) n/a Chr 14: 99.34 – 99.49 Mb PubMed search [2] [3]
Wikidata
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