PIK3AP1

Phosphoinositide 3-kinase adapter protein 1 is an enzyme that in humans is encoded by the PIK3AP1 gene.^[5][6][7]

PIK3AP1
Identifiers
Aliases	PIK3AP1, BCAP, phosphoinositide-3-kinase adaptor protein 1
External IDs	OMIM: 607942; MGI: 1933177; HomoloGene: 12848; GeneCards: PIK3AP1; OMA:PIK3AP1 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q24.1 Start 96,593,315 bp[1] End 96,720,514 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C3 Start 41,260,816 bp[2] End 41,373,541 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in parotid gland pancreatic epithelial cell monocyte pancreatic ductal cell mucosa of ileum appendix blood trabecular bone bone marrow granulocyte Top expressed in granulocyte submandibular gland spleen vestibular sensory epithelium blood Paneth cell liver right lung lobe vestibular membrane of cochlear duct lymph node More reference expression data BioGPS n/a
Gene ontology Molecular function phosphatidylinositol 3-kinase regulatory subunit binding identical protein binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity signaling receptor binding Cellular component cytoplasm cytosol plasma membrane membrane Biological process positive regulation of phosphatidylinositol 3-kinase signaling toll-like receptor 9 signaling pathway toll-like receptor 2 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 7 signaling pathway regulation of inflammatory response phosphatidylinositol phosphate biosynthetic process positive regulation of protein kinase B signaling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 118788 83490 Ensembl ENSG00000155629 ENSMUSG00000025017 UniProt Q6ZUJ8 Q9EQ32 RefSeq (mRNA) NM_152309 NM_031376 RefSeq (protein) NP_689522 NP_113553 Location (UCSC) Chr 10: 96.59 – 96.72 Mb Chr 19: 41.26 – 41.37 Mb PubMed search [3] [4]
Wikidata
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