PIK3C2G

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

PIK3C2G

Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide is an enzyme that in humans is encoded by the PIK3C2G gene.[5][6]

Quick Facts Available structures, PDB ...
PIK3C2G
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPIK3C2G, PI3K-C2-gamma, PI3K-C2GAMMA, phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
External IDsOMIM: 609001; MGI: 1203730; HomoloGene: 3362; GeneCards: PIK3C2G; OMA:PIK3C2G - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001288772
NM_001288774
NM_004570

NM_011084
NM_207683

RefSeq (protein)

NP_001275701
NP_001275703
NP_004561

NP_035214
NP_997566

Location (UCSC)Chr 12: 18.24 – 18.65 MbChr 6: 139.56 – 139.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined.[6]

References

Further reading

Loading related searches...

Wikiwand - on

Seamless Wikipedia browsing. On steroids.