PIM3

Serine/threonine-protein kinase pim-3 is an enzyme that in humans is encoded by the PIM3 gene.^[5]

PIM3
Identifiers
Aliases	PIM3, pim-3, Pim-3 proto-oncogene, serine/threonine kinase
External IDs	OMIM: 610580; MGI: 1355297; HomoloGene: 56955; GeneCards: PIM3; OMA:PIM3 - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.33 Start 49,960,768 bp[1] End 49,964,072 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E3 Start 88,746,389 bp[2] End 88,749,929 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in olfactory zone of nasal mucosa skin of abdomen skin of leg body of stomach upper lobe of left lung minor salivary glands left uterine tube subcutaneous adipose tissue right lung gastrocnemius muscle Top expressed in Paneth cell lacrimal gland vestibular membrane of cochlear duct cumulus cell parotid gland motor neuron facial motor nucleus substantia nigra endothelial cell of lymphatic vessel renal corpuscle More reference expression data BioGPS n/a
Gene ontology Molecular function kinase activity transferase activity nucleotide binding protein serine/threonine kinase activity protein kinase activity protein binding ATP binding Cellular component cytoplasm cytosol Biological process protein autophosphorylation protein phosphorylation cell cycle negative regulation of insulin secretion involved in cellular response to glucose stimulus negative regulation of apoptotic process phosphorylation regulation of mitotic cell cycle apoptotic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 415116 223775 Ensembl ENSG00000198355 ENSMUSG00000035828 UniProt Q86V86 P58750 RefSeq (mRNA) NM_001001852 NM_145478 RefSeq (protein) NP_001001852 NP_663453 Location (UCSC) Chr 22: 49.96 – 49.96 Mb Chr 15: 88.75 – 88.75 Mb PubMed search [3] [4]
Wikidata
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