PITPNM1

Membrane-associated phosphatidylinositol transfer protein 1 is a protein that in humans is encoded by the PITPNM1 gene.^[4][5]

PITPNM1
Identifiers
Aliases	PITPNM1, DRES9, NIR2, PITPNM, RDGB, RDGB1, RDGBA, RDGBA1, Rd9, phosphatidylinositol transfer protein membrane associated 1
External IDs	OMIM: 608794; MGI: 1197524; HomoloGene: 3608; GeneCards: PITPNM1; OMA:PITPNM1 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q13.2 Start 67,491,768 bp[1] End 67,506,263 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte right uterine tube olfactory zone of nasal mucosa anterior pituitary right frontal lobe right hemisphere of cerebellum monocyte lateral nuclear group of thalamus cingulate gyrus anterior cingulate cortex n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding phosphatidylinositol transfer activity phosphatidylcholine binding phosphatidylinositol binding phosphatidic acid binding phospholipid transporter activity calcium ion binding receptor tyrosine kinase binding phosphatidylcholine transporter activity Cellular component Golgi cisterna membrane lipid droplet Golgi apparatus midbody cleavage furrow intracellular anatomical structure endoplasmic reticulum membrane membrane endoplasmic reticulum cytoplasm cytosol cytoplasmic ribonucleoprotein granule microtubule organizing center cell body Biological process protein transport brain development lipid metabolism phototransduction phosphatidylinositol biosynthetic process phospholipid transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9600 18739 Ensembl ENSG00000110697 ENSMUSG00000024851 UniProt O00562 O35954 RefSeq (mRNA) NM_001130848 NM_004910 NM_001136078 NM_008851 RefSeq (protein) NP_001124320 NP_004901 NP_032877 Location (UCSC) Chr 11: 67.49 – 67.51 Mb n/a PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Function

PITPNM1 belongs to a family of proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein.[supplied by OMIM]^[5]

Interactions

PITPNM1 has been shown to interact with PTK2B.^[6]