PLA2G12A

Group XIIA secretory phospholipase A₂ is an enzyme that in humans is encoded by the PLA2G12A gene.^[5][6]

PLA2G12A
Identifiers
Aliases	PLA2G12A, GXII, PLA2G12, ROSSY, phospholipase A2 group XIIA
External IDs	OMIM: 611652; MGI: 1913600; HomoloGene: 11328; GeneCards: PLA2G12A; OMA:PLA2G12A - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q25 Start 109,709,989 bp[1] End 109,730,070 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 G3 Start 129,672,255 bp[2] End 129,689,474 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of arm endothelial cell cardiac muscle tissue of right atrium myocardium of left ventricle inferior ganglion of vagus nerve renal medulla pons medulla oblongata parietal pleura subthalamic nucleus Top expressed in Ileal epithelium plantaris muscle interventricular septum soleus muscle parotid gland extensor digitorum longus muscle extraocular muscle lacrimal gland thoracic diaphragm ankle joint More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding calcium-dependent phospholipase A2 activity metal ion binding hydrolase activity phospholipase A2 activity Cellular component cytoplasm Golgi apparatus intracellular anatomical structure extracellular region endoplasmic reticulum Biological process phosphatidic acid biosynthetic process phosphatidylserine acyl-chain remodeling phosphatidylethanolamine acyl-chain remodeling lipid metabolism phosphatidylinositol acyl-chain remodeling lipid catabolic process phosphatidylglycerol acyl-chain remodeling phosphatidylcholine acyl-chain remodeling phospholipid metabolic process arachidonic acid secretion biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81579 66350 Ensembl ENSG00000123739 ENSMUSG00000027999 UniProt Q9BZM1 Q542Y6 Q9EPR2 RefSeq (mRNA) NM_030821 NM_001286948 NM_023196 NM_183423 RefSeq (protein) NP_110448 NP_110448.2 NP_001273877 NP_075685 NP_904359 Location (UCSC) Chr 4: 109.71 – 109.73 Mb Chr 3: 129.67 – 129.69 Mb PubMed search [3] [4]
Wikidata
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See also

• Phospholipase A₂