PLA2G4B

Phospholipase A₂, group IVB (cytosolic) is an enzyme that in humans is encoded by the PLA2G4B gene.^[3]

JMJD7-PLA2G4B
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 1BCI, 1CJY, 1RLW
Identifiers
Aliases	JMJD7-PLA2G4B, HsT16992, cPLA2-beta, PLA2G4B, JMJD7-PLA2G4B readthrough
External IDs	HomoloGene: 130533; GeneCards: JMJD7-PLA2G4B; OMA:JMJD7-PLA2G4B - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q15.1 Start 41,828,095 bp[1] End 41,848,155 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum skin of abdomen skin of leg granulocyte vagina left ovary right lobe of thyroid gland left lobe of thyroid gland right ovary ectocervix n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding phospholipase activity calcium-dependent phospholipase A2 activity metal ion binding calcium-dependent phospholipid binding hydrolase activity phospholipase A2 activity phospholipase A1 activity lysophospholipase activity Cellular component cytoplasm cytosol endosome early endosome membrane membrane mitochondrial membranes extracellular region mitochondrion mitochondrial inner membrane Biological process phosphatidic acid biosynthetic process phosphatidylserine acyl-chain remodeling phosphatidylethanolamine acyl-chain remodeling glycerophospholipid catabolic process lipid metabolism lipid catabolic process IRE1-mediated unfolded protein response birth phosphatidylglycerol acyl-chain remodeling phospholipid catabolic process phospholipid metabolic process metabolism inflammatory response arachidonic acid metabolic process phosphatidylcholine acyl-chain remodeling calcium-mediated signaling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8681 n/a Ensembl ENSG00000168970 n/a UniProt P0C869 n/a RefSeq (mRNA) NM_001198588 NM_005090 n/a RefSeq (protein) NP_001185517 NP_005081 n/a Location (UCSC) Chr 15: 41.83 – 41.85 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

See also

• Phospholipase A₂