PLEKHM2

Pleckstrin homology domain-containing family M member 2 is a protein that in humans is encoded by the PLEKHM2 gene.^[5]

PLEKHM2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3CXB, 3HW2, 3ZFW
Identifiers
Aliases	PLEKHM2, SKIP, pleckstrin homology and RUN domain containing M2
External IDs	OMIM: 609613; MGI: 1916832; HomoloGene: 19575; GeneCards: PLEKHM2; OMA:PLEKHM2 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.21 Start 15,684,320 bp[1] End 15,734,769 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D3 Start 141,353,045 bp[2] End 141,392,210 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right frontal lobe apex of heart cingulate gyrus anterior cingulate cortex gastrocnemius muscle muscle of thigh prefrontal cortex right hemisphere of cerebellum stromal cell of endometrium Brodmann area 9 Top expressed in interventricular septum primary visual cortex superior frontal gyrus muscle of thigh cerebellar cortex genital tubercle lip spermatid dentate gyrus of hippocampal formation granule cell neural layer of retina More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding kinesin binding Cellular component cytoplasm endosome membrane Biological process positive regulation of membrane tubulation Golgi organization regulation of protein localization lysosome localization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23207 69582 Ensembl ENSG00000116786 ENSMUSG00000028917 UniProt Q8IWE5 Q80TQ5 RefSeq (mRNA) NM_015164 NM_001033150 NM_001347237 RefSeq (protein) NP_055979 NP_001028322 NP_001334166 Location (UCSC) Chr 1: 15.68 – 15.73 Mb Chr 4: 141.35 – 141.39 Mb PubMed search [3] [4]
Wikidata
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