PLXNA3

Plexin-A3 is a protein that in humans is encoded by the PLXNA3 gene.^[5][6][7]

PLXNA3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3IG3
Identifiers
Aliases	PLXNA3, 6.3, HSSEXGENE, PLXN3, PLXN4, XAP-6, plexin A3
External IDs	OMIM: 300022; MGI: 107683; HomoloGene: 7481; GeneCards: PLXNA3; OMA:PLXNA3 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq28 Start 154,458,281 bp[1] End 154,477,779 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X A7.3|X 38.0 cM Start 73,372,672 bp[2] End 73,388,295 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary stromal cell of endometrium right hemisphere of cerebellum ganglionic eminence left ovary right ovary tibial nerve right coronary artery right uterine tube sural nerve Top expressed in ventricular zone ganglionic eminence genital tubercle motor neuron female urethra lateral amygdaloid nucleus Anterior olfactory nucleus perirhinal cortex entorhinal cortex medial amygdaloid nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding transmembrane signaling receptor activity semaphorin receptor activity Cellular component integral component of membrane membrane intracellular membrane-bounded organelle plasma membrane semaphorin receptor complex cell junction nucleus integral component of plasma membrane Biological process regulation of axon extension involved in axon guidance negative chemotaxis negative regulation of axon extension involved in axon guidance neuron projection extension multicellular organism development neuron projection guidance branchiomotor neuron axon guidance positive regulation of cytoskeleton organization pyramidal neuron development facial nerve structural organization hippocampus development trigeminal nerve structural organization semaphorin-plexin signaling pathway signal transduction axon guidance semaphorin-plexin signaling pathway involved in axon guidance negative regulation of cell adhesion regulation of cell shape regulation of cell migration regulation of GTPase activity positive regulation of axonogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55558 18846 Ensembl ENSG00000130827 ENSMUSG00000031398 UniProt P51805 P70208 RefSeq (mRNA) NM_017514 NM_008883 NM_001358129 RefSeq (protein) NP_059984 NP_032909 NP_001345058 Location (UCSC) Chr X: 154.46 – 154.48 Mb Chr X: 73.37 – 73.39 Mb PubMed search [3] [4]
Wikidata
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