PPAPDC1A

Phosphatidate phosphatase PPAPDC1A also known as phosphatidic acid phosphatase type 2 domain containing 1A is an enzyme that in humans is encoded by the PPAPDC1A gene.^[5] PPAPDC1A has phosphatidate phosphatase activity.^[6]

PLPP4
Identifiers
Aliases	PLPP4, DPPL2, PPAPDC1, PPAPDC1A, phospholipid phosphatase 4
External IDs	MGI: 2685936; HomoloGene: 38751; GeneCards: PLPP4; OMA:PLPP4 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q26.12 Start 120,457,227 bp[1] End 120,592,065 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 128,858,755 bp[2] End 128,993,136 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte Hypothalamus hippocampus proper substantia nigra C1 segment Amygdala Pons stromal cell of endometrium putamen Top expressed in olfactory bulb Hypothalamus embryo embryo dentate gyrus of hippocampal formation granule cell Mesencephalon Cerebellum cerebellar cortex striatum of neuraxis primary visual cortex More reference expression data BioGPS n/a
Gene ontology Molecular function hydrolase activity phosphatidate phosphatase activity identical protein binding phosphatase activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process phospholipid metabolic process phospholipid dephosphorylation Fc-gamma receptor signaling pathway involved in phagocytosis signal transduction blastocyst hatching Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 196051 381925 Ensembl ENSG00000203805 ENSMUSG00000070366 UniProt Q5VZY2 Q0VBU9 RefSeq (mRNA) NM_001030059 NM_001318166 NM_001318167 NM_001318168 NM_001318169 NM_001080963 RefSeq (protein) NP_001025230 NP_001305095 NP_001305096 NP_001305097 NP_001305098 NP_001074432 Location (UCSC) Chr 10: 120.46 – 120.59 Mb Chr 7: 128.86 – 128.99 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse