PPM1K

Protein phosphatase 1K, mitochondrial is an enzyme that in humans is encoded by the PPM1K gene.^[5][6]

PPM1K
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2IQ1, 4DA1
Identifiers
Aliases	PPM1K, BDP, MSUDMV, PP2Ckappa, PP2Cm, PTMP, UG0882E07, protein phosphatase, Mg2+/Mn2+ dependent 1K
External IDs	OMIM: 611065; MGI: 2442111; HomoloGene: 36819; GeneCards: PPM1K; OMA:PPM1K - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q22.1 Start 88,257,620 bp[1] End 88,284,769 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 B3 Start 57,506,502 bp[2] End 57,535,468 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in myocardium of left ventricle cardiac muscle tissue of right atrium right ventricle postcentral gyrus middle temporal gyrus internal globus pallidus superior frontal gyrus palpebral conjunctiva pars compacta pars reticulata Top expressed in piriform cortex interventricular septum medial geniculate nucleus left lobe of liver Region I of hippocampus proper globus pallidus myocardium of ventricle inferior colliculi lateral geniculate nucleus parotid gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein serine/threonine phosphatase activity protein binding catalytic activity phosphoprotein phosphatase activity hydrolase activity metal ion binding cation binding Cellular component mitochondrial matrix mitochondrion Biological process protein dephosphorylation branched-chain amino acid catabolic process positive regulation of pyruvate dehydrogenase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 152926 243382 Ensembl ENSG00000163644 ENSMUSG00000037826 UniProt Q8N3J5 Q8BXN7 RefSeq (mRNA) NM_152542 NM_175523 RefSeq (protein) NP_689755 NP_780732 Location (UCSC) Chr 4: 88.26 – 88.28 Mb Chr 6: 57.51 – 57.54 Mb PubMed search [3] [4]
Wikidata
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