PPP6C

Serine/threonine-protein phosphatase 6 catalytic subunit is an enzyme that in humans is encoded by the PPP6C gene.^[5][6]

PPP6C
Identifiers
Aliases	PPP6C, PP6, PP6C, protein phosphatase 6 catalytic subunit
External IDs	OMIM: 612725; MGI: 1915107; HomoloGene: 68273; GeneCards: PPP6C; OMA:PPP6C - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q33.3 Start 125,146,573 bp[1] End 125,189,939 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 B Start 39,084,366 bp[2] End 39,116,463 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte sperm secondary oocyte gingival epithelium parotid gland buccal mucosa cell palpebral conjunctiva amniotic fluid deltoid muscle epithelium of nasopharynx Top expressed in medullary collecting duct tail of embryo genital tubercle renal corpuscle triceps brachii muscle endocardial cushion vastus lateralis muscle spermatid temporal muscle morula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding phosphoprotein phosphatase activity hydrolase activity metal ion binding protein serine/threonine phosphatase activity Cellular component cytoplasm cytosol Golgi membrane mitochondrion Biological process cell cycle COPII vesicle coating protein dephosphorylation immune system process innate immune response G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5537 67857 Ensembl ENSG00000119414 ENSMUSG00000026753 UniProt O00743 Q9CQR6 RefSeq (mRNA) NM_001123355 NM_001123369 NM_002721 NM_024209 RefSeq (protein) NP_001116827 NP_001116841 NP_002712 NP_077171 Location (UCSC) Chr 9: 125.15 – 125.19 Mb Chr 2: 39.08 – 39.12 Mb PubMed search [3] [4]
Wikidata
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Interactions

PPP6C has been shown to interact with IGBP1.^[7][8]