PRKACG

cAMP-dependent protein kinase catalytic subunit gamma is an enzyme that in humans is encoded by the PRKACG gene.^[3][4][5]

PRKACG
Identifiers
Aliases	PRKACG, KAPG, PKACg, BDPLT19, protein kinase cAMP-activated catalytic subunit gamma
External IDs	OMIM: 176893; HomoloGene: 55677; GeneCards: PRKACG; OMA:PRKACG - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q21.11 Start 69,012,504 bp[1] End 69,014,113 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm left testis right testis buccal mucosa cell amniotic fluid tendon of biceps brachii muscular system muscle muscle skeletal muscle n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity cAMP-dependent protein kinase activity kinase activity ATP binding protein serine/threonine kinase activity Cellular component nucleoplasm cytosol intercellular bridge ciliary base Biological process activation of protein kinase A activity male gonad development phosphorylation cellular response to glucagon stimulus blood coagulation stimulatory C-type lectin receptor signaling pathway protein phosphorylation spermatogenesis renal water homeostasis high-density lipoprotein particle assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5568 n/a Ensembl ENSG00000165059 n/a UniProt P22612 n/a RefSeq (mRNA) NM_002732 n/a RefSeq (protein) NP_002723 n/a Location (UCSC) Chr 9: 69.01 – 69.01 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit.^[5]

Interactions

PRKACG has been shown to interact with Ryanodine receptor 2.^[6]