PRPF40A

Pre-mRNA-processing factor 40 homolog A is a protein that in humans is encoded by the PRPF40A gene.^[5][6][7]

PRPF40A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1UZC, 1YWI, 1YWJ, 1ZR7, 2CQN, 2DYF, 2KZG, 2L5F, 2L9V, 2LKS
Identifiers
Aliases	PRPF40A, FBP-11, FBP11, FLAF1, FNBP3, HIP-10, HIP10, HYPA, NY-REN-6, Prp40, pre-mRNA processing factor 40 homolog A
External IDs	OMIM: 612941; MGI: 1860512; HomoloGene: 6377; GeneCards: PRPF40A; OMA:PRPF40A - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q23.3 Start 152,651,593 bp[1] End 152,718,012 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 C1.1 Start 53,134,704 bp[2] End 53,191,284 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte caput epididymis corpus epididymis tail of epididymis Achilles tendon epithelium of nasopharynx trabecular bone mucosa of paranasal sinus oral cavity visceral pleura Top expressed in tail of embryo genital tubercle spermatid spermatocyte ventricular zone Rostral migratory stream zygote abdominal wall embryo epiblast More reference expression data BioGPS More reference expression data
Gene ontology Molecular function proline-rich region binding protein binding RNA binding Cellular component nuclear matrix U1 snRNP U2-type prespliceosome membrane nucleus nucleoplasm cytosol nuclear speck Biological process cell division cell cycle mRNA processing regulation of cytokinesis cell migration cytoskeleton organization RNA splicing regulation of cell shape mRNA splicing, via spliceosome mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55660 56194 Ensembl ENSG00000196504 ENSMUSG00000061136 UniProt O75400 Q9R1C7 RefSeq (mRNA) NM_017892 NM_001354432 NM_001354431 NM_001365596 NM_001365597 NM_001365598 NM_001365599 NM_001365600 NM_001365601 NM_001365602 NM_001365603 NM_001365604 NM_001365605 NM_001395472 NM_001395473 NM_001395475 NM_001395476 NM_001395477 NM_001395478 NM_001395479 NM_001395480 NM_001395481 NM_001395482 NM_001395483 NM_001395488 NM_018785 RefSeq (protein) NP_060362 NP_001341361 NP_001341360 NP_001352525 NP_001352526 NP_001352527 NP_001352528 NP_001352529 NP_001352530 NP_001352531 NP_001352532 NP_001352533 NP_001352534 NP_061255 NP_001357944 NP_001357945 NP_001357946 NP_001357947 NP_001357948 NP_001357949 Location (UCSC) Chr 2: 152.65 – 152.72 Mb Chr 2: 53.13 – 53.19 Mb PubMed search [3] [4]
Wikidata
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Interactions

PRPF40A has been shown to interact with Huntingtin.^[8]