PRSS23

Serine protease 23 is an enzyme that in humans is encoded by the PRSS23 gene.^[5]

PRSS23
Identifiers
Aliases	PRSS23, SIG13, SPUVE, ZSIG13, protease, serine 23, serine protease 23
External IDs	OMIM: 618376; MGI: 1923703; HomoloGene: 5191; GeneCards: PRSS23; OMA:PRSS23 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q14.2 Start 86,791,059 bp[1] End 86,952,910 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 D3 Start 89,156,991 bp[2] End 89,176,395 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in nasal epithelium mucosa of paranasal sinus olfactory zone of nasal mucosa cartilage tissue right coronary artery saphenous vein decidua urethra epithelium of bronchus bronchial epithelial cell Top expressed in endothelial cell of lymphatic vessel cervix stroma of bone marrow conjunctival fornix seminal vesicula tunica media of zone of aorta cornea vestibular sensory epithelium calvaria submandibular gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function peptidase activity serine-type peptidase activity serine-type endopeptidase activity hydrolase activity Cellular component extracellular region extracellular exosome nucleus extracellular space endoplasmic reticulum lumen Biological process proteolysis post-translational protein modification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11098 76453 Ensembl ENSG00000150687 ENSMUSG00000039405 UniProt O95084 Q9D6X6 RefSeq (mRNA) NM_001293178 NM_001293179 NM_001293180 NM_007173 NM_029614 NM_001360752 NM_001360753 NM_001360754 NM_001360755 NM_001360756 NM_001384148 NM_001384151 RefSeq (protein) NP_001280108 NP_001280109 NP_009104 NP_083890 NP_001347681 NP_001347682 NP_001347683 NP_001347684 NP_001347685 NP_001371077 NP_001371080 Location (UCSC) Chr 11: 86.79 – 86.95 Mb Chr 7: 89.16 – 89.18 Mb PubMed search [3] [4]
Wikidata
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This gene encodes a member of the trypsin family of serine proteases. Mouse studies found a decrease of mRNA levels after ovulation was induced. This gene seems to be highly conserved in vertebrates and may be an important ovarian protease.^[5]