PRSS55

Serine protease 55 is a protein that in humans is encoded by the PRSS55 gene. ^[5]

PRSS55
Identifiers
Aliases	PRSS55, CT153, T-SP1, TSP1, UNQ9391, protease, serine 55, serine protease 55
External IDs	OMIM: 615144; MGI: 1918287; HomoloGene: 51233; GeneCards: PRSS55; OMA:PRSS55 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8p23.1 Start 10,525,532 bp[1] End 10,554,166 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 D1 Start 64,075,438 bp[2] End 64,090,162 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad right testis left testis cerebellar cortex cerebellar hemisphere right hemisphere of cerebellum primary visual cortex amygdala Brodmann area 9 C1 segment Top expressed in seminiferous tubule spermatid spermatocyte gastrula lacrimal gland embryo quadriceps femoris muscle free upper limb intercostal muscle major salivary gland More reference expression data BioGPS n/a
Gene ontology Molecular function peptidase activity serine-type peptidase activity hydrolase activity serine-type endopeptidase activity Cellular component cytoplasm integral component of membrane cytosol membrane Biological process proteolysis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 203074 71037 Ensembl ENSG00000184647 ENSG00000285141 ENSMUSG00000034623 UniProt Q6UWB4 Q14BX2 RefSeq (mRNA) NM_001197020 NM_198464 NM_001081063 RefSeq (protein) NP_001183949 NP_940866 NP_001074532 NP_001366451 NP_001366452 Location (UCSC) Chr 8: 10.53 – 10.55 Mb Chr 14: 64.08 – 64.09 Mb PubMed search [3] [4]
Wikidata
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Function

This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases. The encoded protein is primarily expressed in the Leydig and Sertoli cells of the testis and may be involved in male fertility. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010].