PRUNE2

Protein prune homolog 2 is a protein that in humans is encoded by the PRUNE2 gene.^[5][6]

PRUNE2
Identifiers
Aliases	PRUNE2, A214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367, bA214N16.3, prune homolog 2 (Drosophila), prune homolog 2, prune homolog 2 with BCH domain
External IDs	OMIM: 610691; MGI: 1925004; HomoloGene: 18939; GeneCards: PRUNE2; OMA:PRUNE2 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q21.2 Start 76,611,376 bp[1] End 76,906,114 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 B Start 16,933,482 bp[2] End 17,201,296 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spinal ganglia decidua gastric mucosa Descending thoracic aorta endothelial cell cerebellar vermis popliteal artery tibial arteries ascending aorta corpus callosum Top expressed in facial motor nucleus cerebellar cortex lobe of cerebellum medial dorsal nucleus spinal ganglia cerebellar vermis lumbar spinal ganglion trigeminal ganglion lateral geniculate nucleus medial geniculate nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function pyrophosphatase activity metal ion binding exopolyphosphatase activity Cellular component cytoplasm Biological process apoptotic process polyphosphate catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 158471 353211 Ensembl ENSG00000106772 ENSMUSG00000039126 UniProt Q8WUY3 Q52KR3 RefSeq (mRNA) NM_001308047 NM_001308048 NM_001308049 NM_001308050 NM_001308051 NM_015225 NM_138818 NM_001330680 NM_181348 RefSeq (protein) NP_001294976 NP_001294977 NP_001294978 NP_001294979 NP_001294980 NP_001317609 NP_056040 NP_001294976.1 NP_001294977.1 NP_851993 Location (UCSC) Chr 9: 76.61 – 76.91 Mb Chr 19: 16.93 – 17.2 Mb PubMed search [3] [4]
Wikidata
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