PSCDBP

Cytohesin-interacting protein is a protein that in humans is encoded by the CYTIP gene.^[5][6][7][8]

CYTIP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2Z17
Identifiers
Aliases	CYTIP, B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP, cytohesin 1 interacting protein
External IDs	OMIM: 604448; MGI: 2183535; HomoloGene: 3167; GeneCards: CYTIP; OMA:CYTIP - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q24.1 Start 157,414,619 bp[1] End 157,488,961 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 C1.1 Start 58,019,149 bp[2] End 58,085,544 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood bone marrow cells white blood cell monocyte appendix lymph node granulocyte epithelium of colon epithelium of nasopharynx spleen Top expressed in granulocyte spleen mesenteric lymph nodes right lung lobe thymus blood tibiofemoral joint lactiferous gland bone marrow Paneth cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm endosome cell cortex early endosome nucleoplasm cytosol Biological process regulation of cell adhesion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9595 227929 Ensembl ENSG00000115165 ENSMUSG00000026832 UniProt O60759 Q91VY6 RefSeq (mRNA) NM_004288 NM_139200 RefSeq (protein) NP_004279 NP_631939 Location (UCSC) Chr 2: 157.41 – 157.49 Mb Chr 2: 58.02 – 58.09 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, and it does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells.^[8]