PTGFRN

Prostaglandin F2 receptor negative regulator is a protein that in humans is encoded by the PTGFRN gene.^[5][6] PTGFRN has also been designated as CD315 (cluster of differentiation 315).

PTGFRN
Identifiers
Aliases	PTGFRN, CD315, CD9P-1, EWI-F, FPRP, SMAP-6, prostaglandin F2 receptor inhibitor
External IDs	OMIM: 601204; MGI: 1277114; HomoloGene: 7908; GeneCards: PTGFRN; OMA:PTGFRN - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p13.1 Start 116,909,916 bp[1] End 116,990,353 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F2.2 Start 100,947,548 bp[2] End 101,017,594 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cardiac muscle tissue of right atrium ventricular zone muscle layer of sigmoid colon myocardium of left ventricle right auricle of heart left uterine tube body of uterus olfactory zone of nasal mucosa myometrium right ventricle Top expressed in umbilical cord atrium ventricular zone left lung lobe right lung lobe Gonadal ridge atrioventricular valve molar urinary bladder endocardial cushion More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cell surface Golgi apparatus endoplasmic reticulum membrane endoplasmic reticulum membrane plasma membrane integral component of membrane Biological process lipid droplet organization myoblast fusion involved in skeletal muscle regeneration Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5738 19221 Ensembl ENSG00000134247 ENSMUSG00000027864 UniProt Q9P2B2 Q9WV91 RefSeq (mRNA) NM_020440 NM_011197 RefSeq (protein) NP_065173 NP_035327 Location (UCSC) Chr 1: 116.91 – 116.99 Mb Chr 3: 100.95 – 101.02 Mb PubMed search [3] [4]
Wikidata
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Interactions

PTGFRN has been shown to interact with CD9^[7][8] and CD81.^[7][8]