PWP2

Periodic tryptophan protein 2 homolog is a protein that in humans is encoded by the PWP2 gene.^[5][6]

PWP2
Identifiers
Aliases	PWP2, EHOC-17, PWP2H, UTP1, PWP2 periodic tryptophan protein homolog (yeast), small subunit processome component, PWP2 small subunit processome component
External IDs	OMIM: 601475; MGI: 1341200; HomoloGene: 136786; GeneCards: PWP2; OMA:PWP2 - orthologs
Gene location (Human) Chr. Chromosome 21 (human)[1] Band 21q22.3 Start 44,107,373 bp[1] End 44,131,181 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 C1|10 39.72 cM Start 78,006,743 bp[2] End 78,020,983 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium corpus callosum mucosa of transverse colon gastric mucosa gonad skeletal muscle tissue sural nerve prefrontal cortex right adrenal gland blood Top expressed in primitive streak epiblast primary oocyte otic vesicle secondary oocyte otic placode cumulus cell zygote ventricular zone yolk sac More reference expression data BioGPS More reference expression data
Gene ontology Molecular function snoRNA binding RNA binding Cellular component Pwp2p-containing subcomplex of 90S preribosome nucleus nucleolus small-subunit processome nucleoplasm Biological process ribosomal small subunit assembly maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5822 110816 Ensembl ENSG00000241945 ENSMUSG00000032834 UniProt Q15269 Q8BU03 RefSeq (mRNA) NM_005049 NM_029546 RefSeq (protein) NP_005040 NP_083822 Location (UCSC) Chr 21: 44.11 – 44.13 Mb Chr 10: 78.01 – 78.02 Mb PubMed search [3] [4]
Wikidata
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Function

This protein is involved in the assembly of small subunit of ribosome.^[6]