Phospholysine phosphohistidine inorganic pyrophosphate phosphatase

Phospholysine phosphohistidine inorganic pyrophosphate phosphatase is a protein that in humans is encoded by the LHPP gene. ^[5]

LHPP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2X4D
Identifiers
Aliases	LHPP, HDHD2B, phospholysine phosphohistidine inorganic pyrophosphate phosphatase
External IDs	OMIM: 617231; MGI: 1923679; HomoloGene: 41469; GeneCards: LHPP; OMA:LHPP - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q26.13 Start 124,461,823 bp[1] End 124,617,888 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 132,212,367 bp[2] End 132,308,149 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in C1 segment olfactory bulb tibial nerve inferior olivary nucleus dorsal motor nucleus of vagus nerve hypothalamus amygdala anterior cingulate cortex substantia nigra putamen Top expressed in lip left lobe of liver tail of embryo crypt of lieberkuhn of small intestine internal carotid artery external carotid artery primitive streak muscle of thigh dentate gyrus of hippocampal formation granule cell primary oocyte More reference expression data BioGPS n/a
Gene ontology Molecular function hydrolase activity protein homodimerization activity Inorganic pyrophosphatase magnesium ion binding metal ion binding phosphatase activity protein histidine phosphatase activity Cellular component cytosol nucleus cytoplasm nuclear speck Biological process phosphate-containing compound metabolic process purine ribonucleoside monophosphate biosynthetic process protein dephosphorylation dephosphorylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64077 76429 Ensembl ENSG00000107902 ENSMUSG00000030946 UniProt Q9H008 Q9D7I5 RefSeq (mRNA) NM_001167880 NM_022126 NM_001318331 NM_001318332 NM_029609 RefSeq (protein) NP_001161352 NP_001305260 NP_001305261 NP_071409 NP_083885 Location (UCSC) Chr 10: 124.46 – 124.62 Mb Chr 7: 132.21 – 132.31 Mb PubMed search [3] [4]
Wikidata
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