Polyamine-modulated factor 1

Polyamine-modulated factor 1 is a protein that in humans is encoded by the PMF1 gene.^[5][6]

PMF1
Identifiers
Aliases	PMF1, polyamine modulated factor 1
External IDs	OMIM: 609176; MGI: 1914287; HomoloGene: 5224; GeneCards: PMF1; OMA:PMF1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q22 Start 156,212,993 bp[1] End 156,240,042 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F1 Start 88,301,450 bp[2] End 88,317,638 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh apex of heart right lobe of thyroid gland left lobe of thyroid gland gastrocnemius muscle right auricle of heart ectocervix skin of leg left ventricle granulocyte Top expressed in yolk sac embryo embryo ventricular zone tibiofemoral joint blastocyst internal carotid artery lip morula epiblast More reference expression data BioGPS n/a
Gene ontology Molecular function transcription coactivator activity leucine zipper domain binding protein binding Cellular component chromosome cytosol MIS12/MIND type complex chromosome, centromeric region nucleus kinetochore transcription regulator complex nucleoplasm Golgi apparatus intracellular membrane-bounded organelle nuclear MIS12/MIND complex Biological process chromosome segregation cell division cell cycle regulation of transcription, DNA-templated transcription by RNA polymerase II transcription, DNA-templated positive regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11243 67037 Ensembl ENSG00000160783 ENSMUSG00000028066 UniProt Q6P1K2 Q9CPV5 RefSeq (mRNA) NM_007221 NM_001199653 NM_001199654 NM_025928 NM_001310605 RefSeq (protein) NP_001186582 NP_001186583 NP_009152 NP_001297534 NP_080204 Location (UCSC) Chr 1: 156.21 – 156.24 Mb Chr 3: 88.3 – 88.32 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

Polyamine-modulated factor 1 has been shown to interact with MIS12.^[7][8]