Pridefine

Pridefine
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name 3-(Diphenylmethylidene)-1-ethylpyrrolidine;
CAS Number	5370-41-2;
PubChem CID	31740;
ChemSpider	29434;
UNII	W0394470AX;
CompTox Dashboard (EPA)	DTXSID30201962 ;
Chemical and physical data
Formula	C19H21N
Molar mass	263.384 g·mol−1

Pridefine (AHR-1,118) is a drug which was investigated as an antidepressant in the late 1970s and early 1980s, but was never marketed.^[1] It acts as a balanced reuptake inhibitor of serotonin, dopamine, and norepinephrine, and also has some weak releasing activity.^[1]^[2]^[3]

Quick facts Clinical data, Routes ofadministration ...

In clinical trials pridefine was found to be as efficacious as the tricyclic antidepressants amitriptyline and imipramine in the treatment of major depressive disorder but was much more tolerable in comparison and also had an earlier onset of action.^[1] It has been shown to be effective in the treatment of alcoholism as well.^[1]

See also