Prothipendyl

Prothipendyl
Names
	Preferred IUPAC name N,N-Dimethyl-3-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propan-1-amine
Identifiers
CAS Number	303-69-5 ;
3D model (JSmol)	Interactive image;
ChemSpider	14002 ;
ECHA InfoCard	100.132.989
EC Number	214-958-4;
PubChem CID	14670;
UNII	5O6VWA87VA ;
CompTox Dashboard (EPA)	DTXSID50184389 ;
	InChI InChI=1S/C16H19N3S/c1-18(2)11-6-12-19-13-7-3-4-8-14(13)20-15-9-5-10-17-16(15)19/h3-5,7-10H,6,11-12H2,1-2H3 Key: JTTAUPUMOLRVRA-UHFFFAOYSA-N ; InChI=1/C16H19N3S/c1-18(2)11-6-12-19-13-7-3-4-8-14(13)20-15-9-5-10-17-16(15)19/h3-5,7-10H,6,11-12H2,1-2H3 Key: JTTAUPUMOLRVRA-UHFFFAOYAL;
	SMILES CN(C)CCCN1C2=CC=CC=C2SC3=C1N=CC=C3;
Properties
Chemical formula	C16H19N3S
Molar mass	285.40716
Pharmacology
ATC code	N05AX07 (WHO)
Legal status	BR: Class C1 (Other controlled substances);
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Prothipendyl (brand names Dominal, Timovan, Tolnate), also known as azapromazine or phrenotropin, is an anxiolytic, antiemetic, and antihistamine of the azaphenothiazine group which is marketed in Europe and is used to treat anxiety and agitation in psychotic syndromes.^[2]^[3]^[4]^[5] It differs from promazine only by the replacement of one carbon atom with a nitrogen atom in the tricyclic ring system.^[2]^[3] Prothipendyl is said to not possess antipsychotic effects, and in accordance, appears to be a weaker dopamine receptor antagonist than other phenothiazines.^[6]^[5]

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Synthesis