RAB17

Ras-related protein Rab-17 is a protein that in humans is encoded by the RAB17 gene.^[5][6]

RAB17
Identifiers
Aliases	RAB17, member RAS oncogene family
External IDs	OMIM: 602206; MGI: 104640; HomoloGene: 7502; GeneCards: RAB17; OMA:RAB17 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q37.3 Start 237,574,322 bp[1] End 237,601,614 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 D|1 45.84 cM Start 90,885,855 bp[2] End 90,897,383 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver renal medulla body of pancreas left lobe of thyroid gland right lobe of thyroid gland human kidney mucosa of transverse colon right uterine tube mucosa of ileum jejunal mucosa Top expressed in submandibular gland Paneth cell jejunum medullary collecting duct ileum vestibular membrane of cochlear duct duodenum proximal tubule parotid gland crypt of lieberkuhn of small intestine More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GDP binding GTP binding protein binding GTPase activity Cellular component recycling endosome endosome cell projection membrane melanosome plasma membrane endocytic vesicle intracellular anatomical structure soma recycling endosome membrane dendrite basolateral plasma membrane early endosome apical plasma membrane extracellular exosome Biological process regulation of endocytosis regulation of filopodium assembly regulation of synapse assembly filopodium assembly regulation of dendrite development transcytosis establishment of melanosome localization melanosome transport endocytic recycling protein transport immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor cilium assembly transport intracellular protein transport Rab protein signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64284 19329 Ensembl ENSG00000124839 ENSMUSG00000026304 UniProt Q9H0T7 P35292 RefSeq (mRNA) NM_022449 NM_001159725 NM_008998 RefSeq (protein) NP_071894 NP_071894.1 NP_001153197 NP_033024 Location (UCSC) Chr 2: 237.57 – 237.6 Mb Chr 1: 90.89 – 90.9 Mb PubMed search [3] [4]
Wikidata
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In melanocytic cells RAB17 gene expression may be regulated by MITF.^[7]