RAB33B

Ras-related protein Rab-33B is a protein that in humans is encoded by the RAB33B gene.^[5]

RAB33B
Identifiers
Aliases	RAB33B, SMC2, member RAS oncogene family
External IDs	OMIM: 605950; MGI: 1330805; HomoloGene: 9642; GeneCards: RAB33B; OMA:RAB33B - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q31.1 Start 139,453,232 bp[1] End 139,476,609 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 C Start 51,391,341 bp[2] End 51,403,653 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon saphenous vein urethra Region I of hippocampus proper subthalamic nucleus synovial joint lateral nuclear group of thalamus dorsal motor nucleus of vagus nerve inferior olivary nucleus superficial temporal artery Top expressed in transitional epithelium of urinary bladder sciatic nerve Ileal epithelium iris trigeminal ganglion median eminence ureter vas deferens medullary collecting duct condyle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding nucleotide binding GTP binding GTPase activity Cellular component membrane Golgi lumen Golgi apparatus Golgi membrane presynapse endoplasmic reticulum membrane Biological process negative regulation of constitutive secretory pathway regulation of Golgi organization intra-Golgi vesicle-mediated transport regulation of epithelial cell proliferation regulation of retrograde vesicle-mediated transport, Golgi to ER protein transport skeletal system morphogenesis autophagy regulation of cell growth autophagosome assembly regulation of autophagosome assembly protein localization to Golgi apparatus intracellular protein transport endoplasmic reticulum to Golgi vesicle-mediated transport Rab protein signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83452 19338 Ensembl ENSG00000172007 ENSMUSG00000027739 UniProt Q9H082 O35963 RefSeq (mRNA) NM_031296 NM_016858 RefSeq (protein) NP_112586 NP_058554 Location (UCSC) Chr 4: 139.45 – 139.48 Mb Chr 3: 51.39 – 51.4 Mb PubMed search [3] [4]
Wikidata
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Mutations in this gene have been associated to cases of Dyggve-Melchior-Clausen syndrome.^[6]