RAB38

Ras-related protein Rab-38 is a protein that in humans is encoded by the RAB38 gene.^[5][6]

RAB38
Identifiers
Aliases	RAB38, NY-MEL-1, rrGTPbp, member RAS oncogene family
External IDs	OMIM: 606281; MGI: 1919683; HomoloGene: 21353; GeneCards: RAB38; OMA:RAB38 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q14.2 Start 88,113,251 bp[1] End 88,175,443 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 D3|7 49.19 cM Start 88,079,481 bp[2] End 88,140,780 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gingival epithelium palpebral conjunctiva skin of thigh vulva human penis skin of abdomen hair follicle germinal epithelium oral cavity right adrenal cortex Top expressed in zygote primary oocyte secondary oocyte molar iris epidermis hair follicle skin of external ear skin of abdomen cornea More reference expression data BioGPS More reference expression data
Gene ontology Molecular function AP-2 adaptor complex binding nucleotide binding BLOC-2 complex binding GTP binding GTP-dependent protein binding protein binding AP-3 adaptor complex binding AP-1 adaptor complex binding GTPase activity Cellular component cytoplasm vesicle phagocytic vesicle membrane Golgi apparatus membrane melanosome plasma membrane early endosome phagocytic vesicle endoplasmic reticulum early endosome lumen cytoplasmic vesicle lysosome mitochondrion mitochondria associated membranes cytosol melanosome membrane trans-Golgi network Biological process protein localization to membrane platelet dense granule organization organelle organization phagosome acidification endosome to melanosome transport protein transport melanosome assembly mitochondrion organization vesicle-mediated transport small GTPase mediated signal transduction post-translational protein modification positive regulation of phosphatidylcholine biosynthetic process intracellular protein transport Rab protein signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23682 72433 Ensembl ENSG00000123892 ENSMUSG00000030559 UniProt P57729 Q8QZZ8 RefSeq (mRNA) NM_022337 NM_028238 RefSeq (protein) NP_071732 NP_071732.1 NP_082514 Location (UCSC) Chr 11: 88.11 – 88.18 Mb Chr 7: 88.08 – 88.14 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

In melanocytic cells RAB38 gene expression may be regulated by MITF.^[7]