RAB5B

Ras-related protein Rab-5B is a protein that in humans is encoded by the RAB5B gene.^[5][6][7]

RAB5B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2HEI
Identifiers
Aliases	RAB5B, Rab-5B, member RAS oncogene family
External IDs	OMIM: 179514; MGI: 105938; HomoloGene: 104027; GeneCards: RAB5B; OMA:RAB5B - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.2 Start 55,973,913 bp[1] End 55,996,683 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 D3 Start 128,513,044 bp[2] End 128,532,133 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in C1 segment epithelium of colon skin of leg ectocervix popliteal artery tibial arteries skin of abdomen muscle layer of sigmoid colon gastric mucosa right coronary artery Top expressed in granulocyte dentate gyrus of hippocampal formation granule cell muscle of thigh lip primary visual cortex superior frontal gyrus esophagus neural layer of retina genital tubercle ventricular zone More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GDP binding GTP binding GTP-dependent protein binding protein binding GTPase activity Cellular component endosome membrane melanosome endocytic vesicle intracellular anatomical structure early endosome extracellular exosome plasma membrane secretory granule membrane early endosome membrane intracellular membrane-bounded organelle anchored component of synaptic vesicle membrane Biological process regulation of endocytosis antigen processing and presentation endosome organization plasma membrane to endosome transport protein transport neutrophil degranulation transport intracellular protein transport Rab protein signal transduction endocytosis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5869 19344 Ensembl ENSG00000111540 ENSMUSG00000000711 UniProt P61020 P61021 RefSeq (mRNA) NM_001252036 NM_001252037 NM_002868 NM_011229 NM_177411 RefSeq (protein) NP_001238965 NP_001238966 NP_002859 NP_803130 Location (UCSC) Chr 12: 55.97 – 56 Mb Chr 10: 128.51 – 128.53 Mb PubMed search [3] [4]
Wikidata
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