RAI2

Retinoic acid-induced protein 2 is a protein that in humans is encoded by the RAI2 gene.^[5][6][7]

RAI2
Identifiers
Aliases	RAI2, retinoic acid induced 2
External IDs	OMIM: 300217; MGI: 1344378; HomoloGene: 11034; GeneCards: RAI2; OMA:RAI2 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xp22.13 Start 17,800,049 bp[1] End 17,861,337 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X F4 Start 160,500,065 bp[2] End 160,562,492 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left uterine tube urethra right lung canal of the cervix body of uterus saphenous vein gastric mucosa left ovary vena cava decidua Top expressed in myocardium of ventricle intercostal muscle cumulus cell supraoptic nucleus pineal gland aortic valve muscle of thigh islet of Langerhans Rostral migratory stream ganglionic eminence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding molecular function Cellular component cellular component Biological process embryo development ending in birth or egg hatching Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10742 24004 Ensembl ENSG00000131831 ENSMUSG00000043518 UniProt Q9Y5P3 Q9QVY8 RefSeq (mRNA) NM_001172732 NM_001172739 NM_001172743 NM_021785 NM_001103367 NM_198409 RefSeq (protein) NP_001166203 NP_001166210 NP_001166214 NP_068557 NP_001166210.1 NP_001166214.1 NP_068557.3 NP_001096837 NP_940801 Location (UCSC) Chr X: 17.8 – 17.86 Mb Chr X: 160.5 – 160.56 Mb PubMed search [3] [4]
Wikidata
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This article is about the protein. For the Italian television channel, see Rai 2.

Retinoic acid plays a critical role in development, cellular growth, and differentiation. The specific function of this intronless, retinoic acid-induced gene has not yet been determined; however, it has been suggested to play a role in development. Localization of this gene designates it to be a candidate for diseases such as Nance-Horan syndrome, sensorineural deafness, non-specific X-linked mental retardation, oral-facial-digital syndrome, and Fried syndrome.^[7]