RALBP1

RalA-binding protein 1 is a protein that in humans is encoded by the RALBP1 gene.^[5][6]

RALBP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2KWH, 2KWI, 2MBG
Identifiers
Aliases	RALBP1, RIP1, RLIP1, RLIP76, ralA binding protein 1
External IDs	OMIM: 605801; MGI: 108466; HomoloGene: 4940; GeneCards: RALBP1; OMA:RALBP1 - orthologs
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18p11.22 Start 9,475,009 bp[1] End 9,538,114 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17 E1.1|17 35.26 cM Start 66,155,413 bp[2] End 66,192,793 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in renal medulla nipple spinal ganglia buccal mucosa cell pylorus trigeminal ganglion human penis external globus pallidus mucosa of pharynx pars reticulata Top expressed in zygote primary oocyte Rostral migratory stream secondary oocyte lactiferous gland genital tubercle lacrimal gland tail of embryo esophagus seminal vesicula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding transmembrane transporter activity GTPase activator activity xenobiotic transmembrane transporter activity ATPase-coupled transmembrane transporter activity Cellular component cytosol membrane Biological process endocytosis regulation of small GTPase mediated signal transduction transmembrane transport regulation of GTPase activity chemotaxis positive regulation of GTPase activity signal transduction small GTPase mediated signal transduction xenobiotic transmembrane transport doxorubicin transport xenobiotic detoxification by transmembrane export across the plasma membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10928 19765 Ensembl ENSG00000017797 ENSMUSG00000024096 UniProt Q15311 Q62172 RefSeq (mRNA) NM_006788 NM_001198949 NM_009067 RefSeq (protein) NP_006779 NP_001185878 NP_033093 Location (UCSC) Chr 18: 9.48 – 9.54 Mb Chr 17: 66.16 – 66.19 Mb PubMed search [3] [4]
Wikidata
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Interactions

RALBP1 has been shown to interact with:

• Cyclin B1,^[7]
• HSF1,^[8]
• RALA,^{[5][9][10][11]}
• RALB,^[5][9][12] and
• REPS2.^[11]