RB1CC1

RB1-inducible coiled-coil protein 1 is a protein that in humans is encoded by the RB1CC1 gene.^[5][6][7][8]

RB1CC1
Identifiers
Aliases	RB1CC1, ATG17, CC1, FIP200, PPP1R131, RB1 inducible coiled-coil 1
External IDs	OMIM: 606837; MGI: 1341850; HomoloGene: 7659; GeneCards: RB1CC1; OMA:RB1CC1 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q11.23 Start 52,622,458 bp[1] End 52,745,843 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 A1 Start 6,206,197 bp[2] End 6,276,648 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell bronchial epithelial cell caput epididymis postcentral gyrus corpus epididymis biceps brachii tail of epididymis jejunal mucosa Skeletal muscle tissue of rectus abdominis Skeletal muscle tissue of biceps brachii Top expressed in spermatocyte spermatid zygote morula genital tubercle muscle of thigh granulocyte tail of embryo dentate gyrus of hippocampal formation granule cell secondary oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding protein kinase binding molecular adaptor activity Cellular component phagophore assembly site membrane nuclear membrane Atg1/ULK1 kinase complex phagophore assembly site nucleus cytoplasm endoplasmic reticulum membrane cytosol extrinsic component of membrane lysosome Biological process positive regulation of protein phosphorylation regulation of transcription, DNA-templated negative regulation of extrinsic apoptotic signaling pathway negative regulation of apoptotic process autophagosome assembly transcription, DNA-templated heart development positive regulation of cell size cell cycle liver development macroautophagy autophagy positive regulation of JNK cascade autophagy of mitochondrion autophagy of peroxisome reticulophagy glycophagy regulation of macroautophagy piecemeal microautophagy of the nucleus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9821 12421 Ensembl ENSG00000023287 ENSMUSG00000025907 UniProt Q8TDY2 Q9ESK9 RefSeq (mRNA) NM_001083617 NM_014781 NM_009826 RefSeq (protein) NP_001077086 NP_055596 NP_033956 Location (UCSC) Chr 8: 52.62 – 52.75 Mb Chr 1: 6.21 – 6.28 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

RB1CC1 has been shown to interact with PTK2B,^[9] ASK1^[10] and PTK2.^[9]