RBM6

RNA-binding protein 6 is a protein that in humans is encoded by the RBM6 gene.^[5][6] RBM6 orthologs^[7] have been identified in all mammals for which complete genome data are available.

RBM6
Identifiers
Aliases	RBM6, 3G2, DEF-3, DEF3, HLC-11, NY-LU-12, g16, RNA binding motif protein 6
External IDs	OMIM: 606886; MGI: 1338037; HomoloGene: 31336; GeneCards: RBM6; OMA:RBM6 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.31 Start 49,940,007 bp[1] End 50,100,045 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F1 Start 107,650,758 bp[2] End 107,750,436 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in canal of the cervix gastric mucosa right uterine tube right ovary granulocyte cerebellar hemisphere body of uterus right hemisphere of cerebellum left ovary anterior pituitary Top expressed in genital tubercle tail of embryo neural layer of retina ventricular zone spermatocyte zygote ganglionic eminence morula secondary oocyte superior frontal gyrus More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding protein binding nucleic acid binding RNA binding Cellular component nucleus Biological process RNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10180 19654 Ensembl ENSG00000004534 ENSMUSG00000032582 UniProt P78332 n/a RefSeq (mRNA) NM_001167582 NM_005777 NM_001349190 NM_001349191 NM_001349192 NM_001349193 NM_001349194 NM_011251 NM_029169 RefSeq (protein) NP_001161054 NP_005768 NP_001336119 NP_001336120 NP_001336121 NP_001336122 NP_001336123 n/a Location (UCSC) Chr 3: 49.94 – 50.1 Mb Chr 9: 107.65 – 107.75 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RBM6 splicing factor interacts with the DNA repair protein RAD51, and is also recruited to DNA double-strand breaks where it promotes homologous recombinational repair.^[8]