RBP7

Retinol binding protein 7 is a protein that in humans is encoded by the RBP7 gene. ^[5]

RBP7
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1LPJ
Identifiers
Aliases	RBP7, CRBP4, CRBPIV, retinol binding protein 7, CRABP4
External IDs	OMIM: 608604; MGI: 1890409; HomoloGene: 32521; GeneCards: RBP7; OMA:RBP7 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.22 Start 9,997,206 bp[1] End 10,016,021 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 E2 Start 149,534,144 bp[2] End 149,539,435 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in abdominal fat pericardium subcutaneous adipose tissue monocyte spleen apex of heart granulocyte vena cava gastric mucosa tendon of biceps brachii Top expressed in interventricular septum soleus muscle brown adipose tissue white adipose tissue myocardium of ventricle muscle of thigh right ventricle subcutaneous adipose tissue intercostal muscle left ventricle More reference expression data BioGPS n/a
Gene ontology Molecular function retinol binding protein binding retinoid binding retinal binding lipid binding Cellular component cytoplasm Biological process transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 116362 63954 Ensembl ENSG00000162444 ENSMUSG00000028996 UniProt Q96R05 Q9EPC5 RefSeq (mRNA) NM_052960 NM_022020 RefSeq (protein) NP_443192 NP_071303 Location (UCSC) Chr 1: 10 – 10.02 Mb Chr 4: 149.53 – 149.54 Mb PubMed search [3] [4]
Wikidata
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Function

The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. [provided by RefSeq, Aug 2016].