RDH5

11-cis retinol dehydrogenase is an enzyme that in humans is encoded by the RDH5 gene.^[5][6][7][8]

RDH5
Identifiers
Aliases	RDH5, 9cRDH, HSD17B9, RDH1, SDR9C5, retinol dehydrogenase 5
External IDs	OMIM: 601617; MGI: 1201412; HomoloGene: 2179; GeneCards: RDH5; OMA:RDH5 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.2 Start 55,720,367 bp[1] End 55,724,705 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 D3|10 77.19 cM Start 128,749,462 bp[2] End 128,758,757 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in subcutaneous adipose tissue right lobe of liver mucosa of transverse colon right auricle of heart duodenum muscle layer of sigmoid colon left coronary artery left ventricle lactiferous gland muscle of thigh Top expressed in choroid plexus of fourth ventricle retinal pigment epithelium Epithelium of choroid plexus right kidney lateral ventricle choroid plexus of lateral ventricle dentate gyrus of hippocampal formation granule cell proximal tubule granulocyte choroid More reference expression data BioGPS More reference expression data
Gene ontology Molecular function oxidoreductase activity NAD-retinol dehydrogenase activity protein homodimerization activity androsterone dehydrogenase activity androstan-3-alpha,17-beta-diol dehydrogenase activity Cellular component cell body endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum membrane integral component of membrane Biological process retinol metabolic process visual perception retinoid metabolic process response to stimulus steroid metabolic process lipid metabolism Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5959 19682 Ensembl ENSG00000135437 ENSMUSG00000025350 UniProt Q92781 O55240 RefSeq (mRNA) NM_002905 NM_001199771 NM_134006 NM_001358527 RefSeq (protein) NP_001186700 NP_002896 NP_598767 NP_001345456 Location (UCSC) Chr 12: 55.72 – 55.72 Mb Chr 10: 128.75 – 128.76 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse