REG4

Regenerating islet-derived protein 4 (REG4) is a protein that in humans (Homo sapiens) is encoded by the REG4 gene.^[5][6][7] REG4 is located on Chromosome 1 in humans and is expressed in the proximal gastrointestinal (GI) tract.^[5]

REG4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2KV3
Identifiers
Aliases	REG4, GISP, REG-IV, RELP, regenerating family member 4
External IDs	OMIM: 609846; MGI: 1914959; HomoloGene: 41671; GeneCards: REG4; OMA:REG4 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p12 Start 119,794,017 bp[1] End 119,811,580 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F2.2 Start 98,129,472 bp[2] End 98,144,064 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of ileum duodenum jejunal mucosa body of pancreas mucosa of sigmoid colon rectum pancreatic ductal cell appendix testicle mucosa of transverse colon Top expressed in crypt of lieberkuhn of small intestine left colon Paneth cell duodenum ileum jejunum intestinal villus epithelium of small intestine migratory enteric neural crest cell embryo More reference expression data BioGPS n/a
Gene ontology Molecular function calcium ion binding heparin binding mannan binding carbohydrate binding transmembrane signaling receptor activity Cellular component cytoplasm extracellular region Biological process response to bacterium Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83998 67709 Ensembl ENSG00000134193 ENSMUSG00000027876 UniProt Q9BYZ8 Q9D8G5 RefSeq (mRNA) NM_032044 NM_001159352 NM_001159353 NM_026328 RefSeq (protein) NP_001152824 NP_001152825 NP_114433 NP_080604 Location (UCSC) Chr 1: 119.79 – 119.81 Mb Chr 3: 98.13 – 98.14 Mb PubMed search [3] [4]
Wikidata
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