REXO4

RNA exonuclease 4 is an enzyme that in humans is encoded by the REXO4 gene.^[5][6]

REXO4
Identifiers
Aliases	REXO4, REX4, XPMC2, XPMC2H, REX4 homolog, 3'-5' exonuclease
External IDs	OMIM: 602930; MGI: 2684957; HomoloGene: 133948; GeneCards: REXO4; OMA:REXO4 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q34.2 Start 133,406,059 bp[1] End 133,418,096 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 A3 Start 26,843,575 bp[2] End 26,854,398 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve skeletal muscle tissue gastrocnemius muscle muscle of thigh mucosa of transverse colon ventricular zone granulocyte ganglionic eminence apex of heart body of pancreas Top expressed in Paneth cell fossa condyle internal carotid artery external carotid artery thymus neural layer of retina motor neuron medullary collecting duct facial motor nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity nuclease activity exonuclease activity hydrolase activity nucleic acid binding RNA binding single-stranded DNA binding transcription coactivator activity endonuclease activity 3'-5' exonuclease activity Cellular component nucleolus nucleus nuclear speck Biological process regulation of transcription, DNA-templated nucleic acid phosphodiester bond hydrolysis DNA catabolic process, endonucleolytic DNA catabolic process, exonucleolytic rRNA processing positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57109 227656 Ensembl ENSG00000280706 ENSG00000148300 ENSMUSG00000052406 UniProt Q9GZR2 Q6PAQ4 RefSeq (mRNA) NM_001279349 NM_001279350 NM_001279351 NM_020385 NM_207234 NM_001362876 RefSeq (protein) NP_001266278 NP_001266279 NP_001266280 NP_065118 NP_997117 NP_001349805 Location (UCSC) Chr 9: 133.41 – 133.42 Mb Chr 2: 26.84 – 26.85 Mb PubMed search [3] [4]
Wikidata
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