RGL2

Ral guanine nucleotide dissociation stimulator-like 2 is a protein that in humans is encoded by the RGL2 gene.^[5][6]

RGL2
Identifiers
Aliases	RGL2, HKE1.5, KE1.5, RAB2L, ral guanine nucleotide dissociation stimulator like 2
External IDs	OMIM: 602306; MGI: 107483; HomoloGene: 3494; GeneCards: RGL2; OMA:RGL2 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p21.32 Start 33,291,654 bp[1] End 33,298,942 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 B1 Start 34,148,517 bp[2] End 34,156,661 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spleen right uterine tube pituitary gland anterior pituitary right lobe of thyroid gland fundus left lobe of thyroid gland prostate right adrenal cortex salivary gland Top expressed in granulocyte neural layer of retina lip yolk sac thymus external carotid artery saccule internal carotid artery Rostral migratory stream ventricular zone More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding guanyl-nucleotide exchange factor activity Cellular component intracellular anatomical structure cellular component Biological process small GTPase mediated signal transduction Ras protein signal transduction signal transduction negative regulation of cardiac muscle cell apoptotic process regulation of Ral protein signal transduction positive regulation of phosphatidylinositol 3-kinase signaling regulation of molecular function Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5863 19732 Ensembl ENSG00000228736 ENSG00000237441 ENSG00000237825 ENSG00000224841 ENSG00000206282 n/a ENSMUSG00000041354 UniProt O15211 Q61193 RefSeq (mRNA) NM_001243738 NM_004761 NM_009059 RefSeq (protein) NP_001230667 NP_004752 NP_033085 Location (UCSC) Chr 6: 33.29 – 33.3 Mb Chr 17: 34.15 – 34.16 Mb PubMed search [3] [4]
Wikidata
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Interactions

RGL2 has been shown to interact with HRAS.^[7][8]