RHOBTB3

Rho-related BTB domain-containing protein 3 is a protein that in humans is encoded by the RHOBTB3 gene.^[5][6][7]

RHOBTB3
Identifiers
Aliases	RHOBTB3, Rho related BTB domain containing 3
External IDs	OMIM: 607353; MGI: 1920546; HomoloGene: 8932; GeneCards: RHOBTB3; OMA:RHOBTB3 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q15 Start 95,713,522 bp[1] End 95,824,383 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 C1 Start 76,017,656 bp[2] End 76,092,044 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibia retinal pigment epithelium parotid gland Achilles tendon globus pallidus internal globus pallidus external globus pallidus corpus epididymis placenta caput epididymis Top expressed in hand sciatic nerve otolith organ utricle seminal vesicula medial ganglionic eminence mandibular prominence maxillary prominence abdominal wall vestibular sensory epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding protein binding hydrolase activity ATP binding ATPase activity GTPase activity GTP binding protein kinase binding Cellular component cytoplasm Golgi apparatus extracellular exosome cytosol trans-Golgi network membrane plasma membrane cell cortex cell projection Biological process retrograde transport, endosome to Golgi vesicle-mediated transport male gonad development transport actin filament organization establishment or maintenance of cell polarity Rho protein signal transduction regulation of cell shape actin cytoskeleton organization regulation of actin cytoskeleton organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22836 73296 Ensembl ENSG00000164292 ENSMUSG00000021589 UniProt O94955 Q9CTN4 RefSeq (mRNA) NM_014899 NM_028493 RefSeq (protein) NP_055714 NP_082769 Location (UCSC) Chr 5: 95.71 – 95.82 Mb Chr 13: 76.02 – 76.09 Mb PubMed search [3] [4]
Wikidata
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Function

RHOBTB3 is a member of the evolutionarily conserved RhoBTB subfamily of Rho GTPases. For background information on RHOBTBs, see RHOBTB1 (MIM 607351).[supplied by OMIM]^[7]