RIOX2

Ribosomal oxygenase 2 is a protein that in humans is encoded by the RIOX2 gene.^[5][6]

RIOX2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2XDV, 4BU2, 4BXF
Identifiers
Aliases	RIOX2, MDIG, MINA53, NO52, ROX, MINA, MYC-induced nuclear antigen, MYC induced nuclear antigen, ribosomal oxygenase 2, JMJD10
External IDs	OMIM: 612049; MGI: 1914264; HomoloGene: 12071; GeneCards: RIOX2; OMA:RIOX2 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q11.2 Start 97,941,818 bp[1] End 97,972,457 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 C1.3 Start 59,292,138 bp[2] End 59,312,824 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte right lobe of thyroid gland left lobe of thyroid gland oral cavity buccal mucosa cell internal globus pallidus parotid gland body of pancreas tendon of biceps brachii Skeletal muscle tissue of rectus abdominis Top expressed in otic placode saccule otic vesicle primitive streak epiblast sternocleidomastoid muscle temporal muscle digastric muscle embryo right kidney More reference expression data BioGPS More reference expression data
Gene ontology Molecular function oxidoreductase activity dioxygenase activity metal ion binding histone demethylase activity identical protein binding histone H3-methyl-lysine-4 demethylase activity histone H3-methyl-lysine-36 demethylase activity transcription corepressor activity Cellular component nucleolus transcription regulator complex nucleus nucleoplasm cytosol Biological process regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II transcription, DNA-templated negative regulation of transcription, DNA-templated histone demethylation chromatin remodeling peptidyl-arginine hydroxylation histone H3-K4 demethylation ribosome biogenesis histone H3-K36 demethylation negative regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84864 67014 Ensembl ENSG00000170854 ENSMUSG00000022724 UniProt Q8IUF8 Q8CD15 RefSeq (mRNA) NM_001042533 NM_001261829 NM_032778 NM_153182 NM_025910 RefSeq (protein) NP_001035998 NP_001248758 NP_116167 NP_694822 NP_080186 Location (UCSC) Chr 3: 97.94 – 97.97 Mb Chr 16: 59.29 – 59.31 Mb PubMed search [3] [4]
Wikidata
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