RMRP

RNA component of mitochondrial RNA processing endoribonuclease, also known as RMRP, is a human gene.^[3]

RMRP
Identifiers
Aliases	RMRP, CHH, NME1, RMRPR, RRP2, RNA component of mitochondrial RNA processing endoribonuclease
External IDs	OMIM: 157660; GeneCards: RMRP; OMA:RMRP - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9p13.3 Start 35,657,751 bp[1] End 35,658,018 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in epithelium of colon bone marrow cell sural nerve tonsil corpus callosum Achilles tendon skeletal muscle tissue renal cortex primary visual cortex muscle of thigh n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 6023 n/a Ensembl ENSG00000269900 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 9: 35.66 – 35.66 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Mitochondrial RNA-processing endoribonuclease cleaves mitochondrial RNA complementary to the light chain of the displacement loop at a unique site (Chang and Clayton, 1987). The enzyme is a ribonucleoprotein whose RNA component is a nuclear gene product. The RNA component is the first RNA encoded by a single-copy gene in the nucleus and imported into mitochondria. The RMRP gene is untranslated, i.e., it encodes an RNA not a protein.[supplied by OMIM]^[3]

It is associated with cartilage–hair hypoplasia.^[4]