RNF10

RING finger protein 10 is a protein that in humans is encoded by the RNF10 gene.^[5]

RNF10
Identifiers
Aliases	RNF10, RIE2, ring finger protein 10
External IDs	OMIM: 615998; MGI: 1859162; HomoloGene: 40990; GeneCards: RNF10; OMA:RNF10 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q24.31 Start 120,533,480 bp[1] End 120,577,588 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5 F|5 56.01 cM Start 115,379,471 bp[2] End 115,410,957 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis muscle of thigh gastrocnemius muscle sural nerve stromal cell of endometrium anterior pituitary ventricular zone epithelium of colon blood Top expressed in blood neural layer of retina entorhinal cortex choroid plexus of fourth ventricle lactiferous gland perirhinal cortex CA3 field muscle of thigh superior surface of tongue dentate gyrus of hippocampal formation granule cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding metal ion binding ubiquitin-protein transferase activity Cellular component cytoplasm nucleus Biological process positive regulation of transcription, DNA-templated positive regulation of myelination regulation of transcription, DNA-templated transcription, DNA-templated negative regulation of Schwann cell proliferation positive regulation of transcription by RNA polymerase II protein autoubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9921 50849 Ensembl ENSG00000022840 ENSMUSG00000041740 UniProt Q8N5U6 Q3UIW5 RefSeq (mRNA) NM_014868 NM_001330474 NM_016698 NM_001302448 NM_001302449 RefSeq (protein) NP_001317403 NP_055683 NP_001289377 NP_001289378 NP_057907 Location (UCSC) Chr 12: 120.53 – 120.58 Mb Chr 5: 115.38 – 115.41 Mb PubMed search [3] [4]
Wikidata
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Function

The protein encoded by this gene contains a ring finger motif, which is known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. EST data suggests the existence of multiple alternatively spliced transcript variants, however, their full length nature is not known.^[5]