RNF146

RING finger protein 146 is a protein that in humans is encoded by the RNF146 gene.^[5]

RNF146
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2D8T, 3V3L
Identifiers
Aliases	RNF146, dJ351K20.1, ring finger protein 146
External IDs	OMIM: 612137; MGI: 1915281; HomoloGene: 12227; GeneCards: RNF146; OMA:RNF146 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q22.33 Start 127,266,726 bp[1] End 127,288,567 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 A4 Start 29,220,172 bp[2] End 29,238,438 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar vermis cerebellar hemisphere right hemisphere of cerebellum Skeletal muscle tissue of rectus abdominis gastric mucosa tibia biceps brachii middle temporal gyrus tendon body of uterus Top expressed in interventricular septum motor neuron Region I of hippocampus proper cumulus cell superior cervical ganglion vestibular sensory epithelium primitive streak trigeminal ganglion vestibular membrane of cochlear duct medial ganglionic eminence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding protein binding metal ion binding ubiquitin-protein transferase activity poly-ADP-D-ribose binding ubiquitin protein ligase activity transferase activity Cellular component cytoplasm cytosol nucleus nucleoplasm plasma membrane Biological process positive regulation of canonical Wnt signaling pathway protein K48-linked ubiquitination protein ubiquitination protein autoubiquitination ubiquitin-dependent protein catabolic process Wnt signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81847 68031 Ensembl ENSG00000118518 ENSMUSG00000038876 UniProt Q9NTX7 Q9CZW6 RefSeq (mRNA) NM_001242844 NM_001242845 NM_001242846 NM_001242847 NM_001242848 NM_001242849 NM_001242850 NM_001242851 NM_001242852 NM_030963 NM_001110196 NM_001110197 NM_001110198 NM_001284279 NM_026518 RefSeq (protein) NP_001229773 NP_001229774 NP_001229775 NP_001229776 NP_001229777 NP_001229778 NP_001229779 NP_001229780 NP_001229781 NP_112225 NP_001103666 NP_001103667 NP_001103668 NP_001271208 NP_080794 Location (UCSC) Chr 6: 127.27 – 127.29 Mb Chr 10: 29.22 – 29.24 Mb PubMed search [3] [4]
Wikidata
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