RNF31

RING finger protein 31 is a protein that in humans is encoded by the RNF31 gene.^[5][6]

RNF31
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CT7, 4DBG, 4JUY, 4LJO, 4LJP, 4LJQ, 4OWF, 4OYJ, 4OYK, 4P09, 4P0A, 4P0B, 5EDV
Identifiers
Aliases	RNF31, HOIP, ZIBRA, ring finger protein 31, Paul
External IDs	OMIM: 612487; MGI: 1934704; HomoloGene: 33228; GeneCards: RNF31; OMA:RNF31 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q12 Start 24,146,683 bp[1] End 24,160,660 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 C3 Start 55,829,165 bp[2] End 55,841,150 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spleen granulocyte apex of heart blood muscle of thigh right lobe of thyroid gland anterior pituitary body of pancreas left lobe of thyroid gland right ovary Top expressed in granulocyte neural layer of retina internal carotid artery mesenteric lymph nodes muscle of thigh yolk sac duodenum jejunum thymus superior frontal gyrus More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding ubiquitin-protein transferase activity ubiquitin binding protein binding ubiquitin protein ligase binding transferase activity Cellular component cytoplasm cytosol LUBAC complex CD40 receptor complex cytoplasmic side of plasma membrane Biological process positive regulation of protein targeting to mitochondrion CD40 signaling pathway regulation of tumor necrosis factor-mediated signaling pathway protein polyubiquitination positive regulation of NF-kappaB transcription factor activity positive regulation of I-kappaB kinase/NF-kappaB signaling I-kappaB kinase/NF-kappaB signaling T cell receptor signaling pathway protein linear polyubiquitination protein ubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55072 268749 Ensembl ENSG00000092098 ENSG00000285152 ENSMUSG00000047098 UniProt Q96EP0 Q924T7 RefSeq (mRNA) NM_017999 NM_001310332 NM_194346 RefSeq (protein) NP_001297261 NP_060469 NP_919327 Location (UCSC) Chr 14: 24.15 – 24.16 Mb Chr 14: 55.83 – 55.84 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.^[6]

See also

• RING finger domain