RNGTT

mRNA-capping enzyme is a protein that in humans is encoded by the RNGTT gene.^[5][6][7]

RNGTT
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2C46, 3S24
Identifiers
Aliases	RNGTT, CAP1A, HCE, HCE1, hCAP, RNA guanylyltransferase and 5'-phosphatase
External IDs	OMIM: 603512; MGI: 1329041; HomoloGene: 37851; GeneCards: RNGTT; OMA:RNGTT - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q15 Start 88,609,897 bp[1] End 88,963,618 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 A5 Start 33,310,311 bp[2] End 33,502,614 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cardia nipple pylorus superior surface of tongue mucosa of pharynx ventral tegmental area subthalamic nucleus inferior ganglion of vagus nerve renal medulla trigeminal ganglion Top expressed in tail of embryo genital tubercle extraocular muscle zygote spermatocyte ventricular zone abdominal wall epiblast embryo thymus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein tyrosine/serine/threonine phosphatase activity phosphatase activity protein tyrosine phosphatase activity polynucleotide 5'-phosphatase activity RNA guanylyltransferase activity triphosphatase activity nucleotidyltransferase activity mRNA guanylyltransferase activity catalytic activity hydrolase activity nucleotide binding GTP binding transferase activity protein binding Cellular component nucleus nucleoplasm Biological process mRNA processing RNA processing protein dephosphorylation transcription by RNA polymerase II dephosphorylation 7-methylguanosine mRNA capping metabolism peptidyl-tyrosine dephosphorylation polynucleotide 5' dephosphorylation viral process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8732 24018 Ensembl ENSG00000111880 ENSMUSG00000028274 UniProt O60942 O55236 RefSeq (mRNA) NM_001286426 NM_001286428 NM_003800 NM_011884 NM_001305273 RefSeq (protein) NP_001273355 NP_001273357 NP_003791 NP_001292202 NP_036014 Location (UCSC) Chr 6: 88.61 – 88.96 Mb Chr 4: 33.31 – 33.5 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse